Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293641 | 0.78 | CA2 (0.48) | CA2CA12CA1CA14 | |
| SCHEMBL14891731 | 0.78 | MEN1 (0.38) | — | |
| SCHEMBL291781 | 0.76 | CA2 (0.46) | CA2CA12CA1CA14 | |
| SCHEMBL1806550 | 0.76 | CHRM2 (0.48) | CA2CA12CA1CA14 | |
| SCHEMBL8944291 | 0.74 | DNM1 (0.48) | CA2CA12CA1CA14 | |
| SCHEMBL8646114 | 0.74 | DNM1 (0.48) | CA2CA12CA1CA14 | |
| SCHEMBL2887901 | 0.74 | DNM1 (0.48) | CA2CA12CA1CA14 | |
| SCHEMBL291433 | 0.74 | DNM1 (0.48) | CA2CA12CA1CA14 | |
| SCHEMBL6766174 | 0.74 | — | — | |
| SCHEMBL24392100 | 0.73 | CA12 (0.33) | CA2CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018233-A1 | MACROCYCLIC INDOLE DERIVATIVES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS (IE) | 2010-02-18 | — | — | WO | disclosed |