Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14892638 | 0.93 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL14892794 | 0.91 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL2248793 | 0.84 | — | — | |
| SCHEMBL2853054 | 0.78 | CA2 (0.36) | — | |
| SCHEMBL11989255 | 0.77 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL17327624 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2A | |
| SCHEMBL4374311 | 0.77 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL23838730 | 0.75 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL12967466 | 0.75 | DNM1 (0.46) | MEN1KMT2A | |
| SCHEMBL4374314 | 0.75 | MEN1 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187450-B2 | Substituted pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-2592076-B1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-05-13 | — | — | EP | disclosed |
| CN-103221405-B | Substituted pyridine compound | DAIICHI SANKYO CO LTD | 2015-04-22 | — | — | CN | disclosed |
| US-20140213549-A9 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20140005143-A2 | Substituted PyridineCompound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| CN-103221405-A | Substituted pyridine compound | DAIICHI SANKYO CO LTD | 2013-07-24 | — | — | CN | disclosed |
| EP-2592076-A1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109653-A1 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213549-A9 | Substituted Pyridine Compound | CETP, MTTP, PRCP | MEN1 3088/4885KMT2A 1200/4885 |
| US-20140005143-A2 | Substituted PyridineCompound | CETP, MTTP, CES1 | MEN1 3487/4885KMT2A 1462/4885 |
| US-20130109653-A1 | Substituted Pyridine Compound | CETP, MTTP, PRCP | MEN1 3088/4885KMT2A 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.