SCHEMBL28530573

SCHEMBL28530573

O=C(O)CS(=O)(=O)c1cccc(Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
TSHR P16473 2/20 0.44
AKR1B1 P15121 1/20 0.44
MMP2 P08253 1/20 0.43
MMP7 P09237 1/20 0.43
MMP14 P50281 1/20 0.43
ITGAV P06756 1/20 0.43
APEX1 P27695 1/20 0.42
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 2/20 0.41
ERCC5 P28715 1/20 0.40
FEN1 P39748 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PGR P06401 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28050831 0.85 EGLN1 (0.50) CA12CA1CA2CA9AKR1B1
SCHEMBL14534847 0.77 APEX1 (0.67) CA12CA1CA2CA9TSHR
SCHEMBL2643715 0.77 MCOLN3 (0.50) MCOLN3TSHRAKR1B1LMNAKMT2A
SCHEMBL5377341 0.77 CDC25A (0.43) CA1CA2MCOLN3TSHRITGAV
SCHEMBL28541962 0.75 CA12 (0.49) CA12CA1CA2CA9MMP2
SCHEMBL24814431 0.75 TAS1R3 (0.43) TSHRLMNAL3MBTL1KMT2AALDH1A1
SCHEMBL5111162 0.75 CDC25A (0.45) CA12CA1CA2CA9TSHR
SCHEMBL29986760 0.75 TAS1R3 (0.43) TSHRLMNAL3MBTL1KMT2AALDH1A1
SCHEMBL5115200 0.74 FABP4 (0.46) ITGAVAPEX1LMNAL3MBTL1ALDH1A1
SCHEMBL6884908 0.74 POLB (0.44) CA1CA2MCOLN3TSHRITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105319848-B Colored curable resin composition 住友化学株式会社 2021-03-26 CN disclosed