SCHEMBL28050831

SCHEMBL28050831

O=C(O)CS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.50
MMP2 P08253 1/20 0.50
MMP7 P09237 1/20 0.50
MMP14 P50281 1/20 0.50
ALDH1A1 P00352 2/20 0.49
HTT P42858 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
CYP2C19 P33261 1/20 0.43
GRM4 Q14833 1/20 0.43
AKR1B1 P15121 1/20 0.42
HSD11B1 P28845 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28530573 0.85 CA12 (0.45) EGLN1MMP2MMP7MMP14ALDH1A1
SCHEMBL27475667 0.84 HSD11B1 (0.57) EGLN1ALDH1A1KMT2AHSD11B1ITGAV
SCHEMBL9645793 0.79 PTGES2 (0.44) EGLN1ALDH1A1HTTKMT2ASLC1A3
SCHEMBL2069829 0.79 CA12 (0.54) EGLN1ALDH1A1HTTCA12CA1
SCHEMBL11237304 0.78 ALDH1A1 (0.56) ALDH1A1CA12CA1CA2CA9
SCHEMBL4247243 0.77 PLCG1 (0.56) ALDH1A1LMNAL3MBTL1KMT2AGRM4
SCHEMBL11797264 0.77 SMN1; SMN2 (0.66) MMP2MMP7MMP14ALDH1A1CA12
SCHEMBL10581834 0.77 MMP2 (0.50) MMP2MMP7MMP14CA12CA1
SCHEMBL16232168 0.77 MMP2 (0.50) MMP2MMP7MMP14ALDH1A1KMT2A
SCHEMBL11883823 0.77 KYNU (0.60) MMP2MMP7MMP14CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105319848-B Colored curable resin composition 住友化学株式会社 2021-03-26 CN disclosed
CN-103365080-B Photosensitive composition 住友化学株式会社 2019-04-26 CN disclosed
CN-107848947-A Fluorochemical, living polymerization initiator, fluoropolymer, the manufacture method of fluoropolymer and anti-corrosion agent composition DIC株式会社 2018-03-27 CN disclosed
CN-102736412-B Photosensitive composition 住友化学株式会社 2017-05-31 CN disclosed
CN-102636957-B Photosensitive composition and compound 住友化学株式会社 2016-06-22 CN disclosed
CN-105319848-A Colored curable resin composition SUMITOMO CHEMICAL CO 2016-02-10 CN disclosed