SCHEMBL28530702

SCHEMBL28530702

Cc1ccc(OC(N)=O)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.43
KMT2A Q03164 3/20 0.43
PKM P14618 1/20 0.42
PPARG P37231 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX15 P16050 1/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 2/20 0.40
CHEK2 O96017 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11137359 0.85 MRGPRX4 (0.47) ACHEMRGPRX4RAB9AHPGDKDM4E
SCHEMBL8367844 0.83 ALDH1A1 (0.49) ACHEMRGPRX4RAB9ANPC1HPGD
SCHEMBL11609948 0.83 KDM4E (0.48) ACHEMRGPRX4RAB9AHPGDKDM4E
SCHEMBL29669768 0.81 L3MBTL1 (0.50) ACHEMRGPRX4RAB9ANPC1HPGD
SCHEMBL473085 0.81 L3MBTL1 (0.50) ACHEMRGPRX4RAB9ANPC1HPGD
SCHEMBL11471602 0.81 TSHR (0.50) ACHESMN1; SMN2KMT2APPARGALOX15
SCHEMBL8861735 0.81 KMT2A (0.57) MRGPRX4HPGDKMT2AMAPTL3MBTL1
SCHEMBL11599855 0.81 MRGPRX4 (0.45) MRGPRX4RAB9AHPGDKDM4EKMT2A
SCHEMBL17355769 0.80 KDM4E (0.46) ACHEMRGPRX4HPGDSMN1; SMN2KDM4E
SCHEMBL29130750 0.79 CYP3A4 (0.50) HPGDSMN1; SMN2KMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109085255-B Method for analyzing and preparing 3- (N-p-toluenesulfonyl-L-alanyloxy) -5-phenylpyrrole and enantiomer thereof by using HPLC method 长春百纯和成医药科技有限公司 2021-03-12 CN claimed
CN-119186531-A Chiral stationary phase derivatized by multi-functional hydroxypropyl-beta-cyclodextrin, preparation method and application thereof 浙江工业大学 2024-12-27 CN disclosed
CN-108956808-B Method for analyzing and preparing diacetyl Corylilactone enantiomer by HPLC (high Performance liquid chromatography) 吉林医药学院 2021-07-20 CN disclosed
CN-109085255-B Method for analyzing and preparing 3- (N-p-toluenesulfonyl-L-alanyloxy) -5-phenylpyrrole and enantiomer thereof by using HPLC method 长春百纯和成医药科技有限公司 2021-03-12 CN disclosed