SCHEMBL473085

SCHEMBL473085

Cc1ccc(OC(N)=O)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
MAPT P10636 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ACHE P22303 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
HPGD P15428 2/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
LMNA P02545 2/20 0.41
GAA P10253 1/20 0.41
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669768 1.00 L3MBTL1 (0.50) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL21551484 0.85 L3MBTL1 (0.48) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL11471602 0.84 TSHR (0.50) MAPTCYP1A2CYP2C9ACHEMEN1
SCHEMBL37754 0.83 L3MBTL1 (0.53) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL3371911 0.82 TRPA1 (0.45) CYP3A4ACHEMEN1KMT2ANPC1
SCHEMBL2191597 0.82 PDE10A (0.45) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL982573 0.82 L3MBTL1 (0.51) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL1799618 0.82 LMNA (0.52) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL6404163 0.82 L3MBTL1 (0.51) L3MBTL1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL28989055 0.81 ABL1 (0.56) L3MBTL1MAPTCYP1A2CYP2C19ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104359990-B A kind of analyzing detecting method of (S) or (R)-4-chloro-3-hydroxyl butyronitrile 浙江海正药业股份有限公司 2016-09-07 CN claimed
CN-102297905-A HPLC (High Performance Liquid Chromatography) method for utilizing chiral column to separate, identify and prepare monomer matter from cucurbitacin mixture 2011-12-28 CN claimed
CN-114751920-A Antitumor compounds 法马马有限公司 2022-07-15 CN disclosed
CN-114736219-A Antitumor compounds 法马马有限公司 2022-07-12 CN disclosed
CN-107207700-B Method for synthesizing polyoxazolidone compound with high stability 科思创德国股份有限公司 2021-04-27 CN disclosed
CN-111004179-B Resolution method of 5' -methoxylapatin 武汉大安制药有限公司 2021-03-09 CN disclosed
CN-111004179-A Resolution method of 5' -methoxylapatin 武汉大安制药有限公司 2020-04-14 CN disclosed
CN-110621678-A Antitumor compounds 法马马有限公司 2019-12-27 CN disclosed
EP-2543736-B1 METHOD FOR PRODUCING 1,5-PENTAMETHYLENE DIISOCYANATE MITSUI CHEMICALS INC (JP) 2019-10-30 EP disclosed
US-10385167-B2 Process for the synthesis of polyoxazolidinone compounds with high stability COVESTRO DEUTSCHLAND AG (DE) 2019-08-20 US disclosed
EP-2592069-B1 METHOD OF PRODUCING TOLUENEDICARBAMATE AND METHOD OF PRODUCING TOLUENEDIISOCYANATE MITSUI CHEMICALS INC (JP) 2019-04-24 EP disclosed
CN-1126628-A Simulated moving bed chromatographic separation process DAICEL CHEM (JP) 1996-07-17 CN disclosed
EP-0606366-A1 SUBSTITUTED PHENSERINES AND PHENYLCARBAMATES OF (-)-ESEROLINE, (-)-N1-NORESEROLINE, AND (-)-N1-BENZYLNORESEROLINE; AS SPECIFIC INHIBITORS OF ACETYLCHOLINESTERASE THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-07-20 EP disclosed
WO-1993006105-A1 SUBSTITUTED PHENSERINES AND PHENYLCARBAMATES OF (-)-ESEROLINE, (-)-N1-NORESEROLINE, AND (-)-N1-BENZYLNORESEROLINE; AS SPECIFIC INHIBITORS OF ACETYLCHOLINESTERASE UNITED STATES GOVERNMENT, AS REPRESENTED BY SECRET (US) 1993-04-01 WO disclosed
US-5075208-A Releasing a photographically useful compound upon reduction FUJI PHOTO FILM CO., LTD. (JP) 1991-12-24 US disclosed
US-4994363-A Silver halide light-sensitive material containing a compound releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 US disclosed
US-4840887-A USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 US disclosed
US-4692550-A Continuous process for thermal splitting of carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4497887-A Thermal development type diazo copying material with hydrophobic resin encapsulated coupler particle Ricoh Compay, Ltd. (JP) 1985-02-05 US disclosed
US-4226883-A Carbamate derivatives and method for manufacture thereof YAMAMOTO IZURU 1980-10-07 US disclosed