Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598439 | 0.94 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2HPGDELANE | |
| SCHEMBL8779173 | 0.90 | KMT2A (0.52) | KMT2AMEN1SMN1; SMN2HPGDELANE | |
| SCHEMBL21991485 | 0.89 | MMP2 (0.49) | KMT2AMEN1SMN1; SMN2HPGDELANE | |
| SCHEMBL1639316 | 0.88 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2HPGDELANE | |
| SCHEMBL21991481 | 0.85 | HPGD (0.68) | KMT2AMEN1SMN1; SMN2HPGDSLC6A3 | |
| SCHEMBL676909 | 0.83 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2HPGDELANE | |
| SCHEMBL7766958 | 0.82 | ESR2 (0.57) | KMT2AMEN1SMN1; SMN2ELANETHRB | |
| SCHEMBL14205190 | 0.82 | LMNA (0.55) | KMT2AMEN1PPARGPPARA | |
| SCHEMBL2058536 | 0.82 | GAA (0.55) | KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL56865 | 0.81 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2HPGDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279770-A | Chiral alpha-polysubstituted-alpha-fluorine-containing homoallylamine compound, and preparation method and application thereof | 武汉大学 | 2021-01-29 | — | — | CN | disclosed |