Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041159 | 0.96 | HTT (0.51) | TSHRHTTHDAC3HDAC1HPGD | |
| SCHEMBL82458 | 0.88 | NPC1 (0.55) | HDAC3HDAC1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL19272602 | 0.84 | TSHR (0.49) | TSHRHTTHDAC3HDAC1HPGD | |
| SCHEMBL25341219 | 0.84 | NPC1 (0.50) | HDAC3HDAC1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6135253 | 0.82 | NPC1 (0.61) | HDAC3HDAC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31174260 | 0.82 | SMN1; SMN2 (0.55) | HDAC3HDAC1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL16670767 | 0.82 | SMN1; SMN2 (0.55) | HDAC3HDAC1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL15768755 | 0.81 | LMNA (0.49) | HDAC3HDAC1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL15768756 | 0.81 | LMNA (0.49) | HDAC3HDAC1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL3621146 | 0.81 | ALDH1A1 (0.48) | HTTHPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108697825-B | Lubricious coatings having surface salt groups | 苏尔莫迪克斯公司 | 2021-02-12 | — | — | CN | disclosed |