Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15768755 | 1.00 | LMNA (0.49) | LMNAALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL29290403 | 0.94 | HDAC1 (0.51) | LMNAALDH1A1NPC1RAB9ANAAA | |
| SCHEMBL82458 | 0.92 | NPC1 (0.55) | LMNAALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL25341219 | 0.88 | NPC1 (0.50) | LMNAALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6135253 | 0.87 | NPC1 (0.61) | LMNAALDH1A1NPC1RAB9ANAAA | |
| SCHEMBL28063078 | 0.84 | NAAA (0.64) | LMNANPC1RAB9ANAAAPOLB | |
| SCHEMBL16670767 | 0.84 | SMN1; SMN2 (0.55) | ALDH1A1HPGDNPC1RAB9ANAAA | |
| SCHEMBL31174260 | 0.84 | SMN1; SMN2 (0.55) | ALDH1A1HPGDNPC1RAB9ANAAA | |
| SCHEMBL20025770 | 0.82 | NAAA (0.54) | LMNAALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL28530862 | 0.81 | TSHR (0.48) | LMNAALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629945-B2 | Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence | SURMODICS, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20140162083-A1 | STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE | SURMODICS, INC. (US) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140162083-A1 | STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE | ITK, NOTUM, ITGAM | LMNA 1406/4885ALDH1A1 1967/4885HPGD 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.