SCHEMBL28530933

SCHEMBL28530933

CSc1ccc(OC2(C)CO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.41
CYP1A1 P04798 3/20 0.39
CYP1A2 P05177 3/20 0.39
CYP1B1 Q16678 3/20 0.39
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
ALDH1A1 P00352 4/20 0.32
MMP1 P03956 1/20 0.32
MMP14 P50281 1/20 0.32
PTGS2 P35354 1/20 0.32
MAOB P27338 1/20 0.32
AOC3 Q16853 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
KCNH2 Q12809 1/20 0.32
GAA P10253 1/20 0.32
LMNA P02545 2/20 0.31
JAK2 O60674 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19583462 0.85 CHRNA1 (0.33)
SCHEMBL7115670 0.76 MAOB (0.38) ALDH1A1MAOB
SCHEMBL10300138 0.73 HPGD (0.42) CYP1A2ALDH1A1SLC6A4TSHR
SCHEMBL9858191 0.69 CYP1A1 (0.51) CYP1A1CYP1A2CYP1B1ALDH1A1MAOB
SCHEMBL1351516 0.67 LMNA (0.51) CYP1A2PTGS2MAOBGAALMNA
SCHEMBL2774995 0.67 CYP1A1 (0.52) CYP1A1CYP1A2CYP1B1ALDH1A1MAOB
SCHEMBL83839 0.65 ALDH1A1 (0.58) CYP1A1CYP1A2CYP1B1NOS3NOS1
SCHEMBL1145983 0.65 CYP1A1 (0.75) CYP1A1CYP1A2CYP1B1ALDH1A1SLC6A4
SCHEMBL11986269 0.65 CYP1A1 (0.75) CYP1A1CYP1A2CYP1B1ALDH1A1SLC6A4
SCHEMBL11045066 0.65 SMN1; SMN2 (0.38) ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112250608-A Synthetic method of 2-phenylacetylene selenol compound 温州医科大学 2021-01-22 CN disclosed