SCHEMBL2774995

SCHEMBL2774995

CSc1ccc(Oc2ccc(SC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP1B1 Q16678 2/20 0.52
SLC6A4 P31645 8/20 0.48
HTR2A P28223 1/20 0.48
KCNH2 Q12809 1/20 0.48
SLC6A2 P23975 3/20 0.44
SLC6A3 Q01959 3/20 0.44
ALDH1A1 P00352 4/20 0.44
HRH3 Q9Y5N1 1/20 0.43
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MAOB P27338 1/20 0.40
AOC3 Q16853 1/20 0.40
LTA4H P09960 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL407203 0.90 TEAD4 (0.54) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL7909500 0.90 LTA4H (0.57) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL4730666 0.88 ALDH1A1 (0.64) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL22167328 0.88 SLC6A4 (0.54) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL4638703 0.88 SLC6A4 (0.54) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL11175207 0.88 MEN1 (0.64) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL16705627 0.88 CYP1A1 (0.44) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL11485483 0.86 SLC6A4 (0.51) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
SCHEMBL8943981 0.86 SLC6A4 (0.45) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A
Hydrochloric Acid SCHEMBL11238778 0.86 ALDH1A1 (0.61) CYP1A1CYP1A2CYP1B1SLC6A4HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303150-A High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2020-06-19 CN claimed
US-11667730-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2023-06-06 US disclosed
CN-116034037-A Thermosensitive recording medium 王子控股株式会社 2023-04-28 CN disclosed
CN-114891071-A Novel polypeptides and therapeutic uses thereof 鸿绪生物科技(嘉善)有限公司 2022-08-12 CN disclosed
CN-111635343-B Preparation method of aryl monosulfide compound 武汉工程大学 2022-05-10 CN disclosed
CN-111690029-B Preparation method of oxalyl coenzyme A 浙江大学 2021-11-12 CN disclosed
CN-113527156-A Oxidation depth controllable thioether oxidation method 扬州大学 2021-10-22 CN disclosed
CN-111303150-B High-efficiency narrow-half-peak-width aggregation state luminescent material 苏州大学 2021-10-19 CN disclosed
US-10982049-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide DIC CORPORATION (JP) 2021-04-20 US disclosed
CN-112552178-A Recycling method of by-product in synthesizing thiobenzol compound 江西天宇化工有限公司 2021-03-26 CN disclosed
EP-1048752-A2 Electrochemically generated organothiating reagents and their use ALBEMARLE CORPORATION (US) 2000-11-02 EP disclosed
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed
EP-0320939-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-06-09 EP disclosed
US-5187055-A Malondianilide coupler improved in fastness of color image produced FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 US disclosed
EP-0403833-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1990-12-27 EP disclosed
EP-0320939-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-21 EP disclosed
EP-0288477-A1 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS THE UPJOHN COMPANY (US) 1988-11-02 EP disclosed
EP-0234113-A1 2,3-Dihydro-1H-phenalene-2-amino compounds as anti-psychotic drugs THE UPJOHN COMPANY (US) 1987-09-02 EP disclosed
WO-1987004153-A1 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS THE UPJOHN COMPANY (US) 1987-07-16 WO disclosed
US-4120866-A REACTING AN AROMATIC COMPOUND WITH A SULFOXIDE BAYER AKTIENGESELLSCHAFT (DE) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667730-B2 Oxime ester compound and photopolymerization initiator containing the same OXER1, CYP4A11, CYP4F11 CYP1A1 23/4885CYP1A2 46/4885CYP1B1 21/4885
US-10982049-B2 Polyarylene sulfide resin and manufacturing method therefor, poly(arylene sulfonium salt) and manufacturing method therefor, and sulfoxide GARS1, ASH2L, SULT1A1 CYP1A1 307/4885CYP1A2 1251/4885CYP1B1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.