Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 13/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530968 | 1.00 | MEN1 (0.46) | MEN1KMT2ACTSAALOX5NR3C2 | |
| SCHEMBL28523142 | 0.89 | MEN1 (0.45) | MEN1KMT2ACTSAALOX5FFAR1 | |
| SCHEMBL28523145 | 0.89 | MEN1 (0.45) | MEN1KMT2ACTSAALOX5FFAR1 | |
| SCHEMBL28519067 | 0.82 | CTSA (0.41) | MEN1KMT2ACTSAALOX5FFAR1 | |
| SCHEMBL28519070 | 0.82 | CTSA (0.41) | MEN1KMT2ACTSAALOX5FFAR1 | |
| SCHEMBL28524919 | 0.82 | CTSA (0.40) | CTSAALOX5FFAR1NPC1RAB9A | |
| SCHEMBL21598766 | 0.79 | ADRB2 (0.40) | CTSAALOX5 | |
| SCHEMBL21598765 | 0.79 | ADRB2 (0.40) | CTSAALOX5 | |
| SCHEMBL9434609 | 0.77 | ALOX5 (0.43) | CTSAALOX5 | |
| SCHEMBL21598768 | 0.75 | MAPT (0.43) | MEN1KMT2ACTSANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615252-A | anti-CD 48 antibodies, antibody drug conjugates and uses thereof | 诺华股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-112437675-A | Antibody drug conjugates for ablating hematopoietic stem cells | 诺华股份有限公司 | 2021-03-02 | — | — | CN | disclosed |