Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 7/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531299 | 0.89 | CTSA (0.39) | CTSAALOX5NPC1RAB9AACHE | |
| SCHEMBL28530968 | 0.82 | MEN1 (0.46) | CTSAALOX5NPC1RAB9AFFAR1 | |
| SCHEMBL28530965 | 0.82 | MEN1 (0.46) | CTSAALOX5NPC1RAB9AFFAR1 | |
| SCHEMBL28524920 | 0.77 | AURKA (0.44) | — | |
| SCHEMBL29643010 | 0.77 | AURKA (0.44) | — | |
| SCHEMBL28101915 | 0.75 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL28524607 | 0.75 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL27765570 | 0.74 | TSHR (0.43) | ACHESMN1; SMN2BCHE | |
| SCHEMBL20541076 | 0.73 | ACHE (0.43) | ACHEBCHE | |
| SCHEMBL27605135 | 0.73 | LOXL2 (0.48) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437675-A | Antibody drug conjugates for ablating hematopoietic stem cells | 诺华股份有限公司 | 2021-03-02 | — | — | CN | disclosed |