Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 9/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23159526 | 0.84 | LMNA (0.41) | NOTUMALDH1A1POLBLMNA | |
| SCHEMBL23159530 | 0.78 | NOTUM (0.33) | NOTUMPDE1APDE1BPDE1C | |
| SCHEMBL23152147 | 0.77 | CNR2 (0.32) | NOTUMALDH1A1BRD4CNR2PDE1A | |
| SCHEMBL28536753 | 0.75 | CCR2 (0.48) | PDE1APDE1BPDE1C | |
| SCHEMBL28541513 | 0.74 | NOTUM (0.40) | NOTUMPTGER4GPR35ALDH1A1 | |
| SCHEMBL28533742 | 0.73 | NOTUM (0.43) | NOTUMPTGER4GPR35ALDH1A1POLB | |
| SCHEMBL28577593 | 0.71 | NOTUM (0.41) | NOTUMPTGER4GPR35BRD4CNR2 | |
| SCHEMBL18938865 | 0.69 | NOTUM (0.41) | NOTUMPTGER4GPR35 | |
| SCHEMBL28839575 | 0.69 | ROCK2 (0.41) | NOTUMPTGER4ALDH1A1CYP1A2 | |
| SCHEMBL28306098 | 0.69 | CCR2 (0.66) | NOTUMPTGER4GPR35ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574230-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-112574230-A | Peptidyl arginine deiminase inhibitors and uses thereof | 南京药捷安康生物科技有限公司 | 2021-03-30 | — | — | CN | disclosed |