Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908921 | 0.91 | MEN1 (0.68) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28531250 | 0.90 | KMT2A (0.67) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28519087 | 0.90 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28525534 | 0.90 | RAB9A (0.67) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28531349 | 0.87 | RAB9A (0.66) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28524552 | 0.84 | KMT2A (0.62) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28148326 | 0.75 | STAT3 (0.56) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| Hydrochloric Acid SCHEMBL28535988 | 0.72 | MEN1 (0.57) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL28518118 | 0.72 | KMT2A (0.55) | SMN1; SMN2MEN1KMT2ARAB9AGAA | |
| SCHEMBL2681128 | 0.72 | STAT3 (1.00) | SMN1; SMN2MEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | claimed |
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | disclosed |