SCHEMBL28532142

SCHEMBL28532142

C=CC[PH](=O)NC1CCS(=O)(=O)C1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.37
HTT P42858 2/20 0.35
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28542489 0.79 SMN1; SMN2 (0.43) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL5111267 0.73 MITF (0.50) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL28532148 0.71 SMN1; SMN2 (0.50) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL31070988 0.70
SCHEMBL28534648 0.68 MAPT (0.46) SMN1; SMN2ALDH1A1MAPTLMNAGAA
SCHEMBL28546693 0.68 MITF (0.46) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL4802583 0.66 SMN1; SMN2 (0.48) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL11200026 0.65 SMN1; SMN2 (0.52) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL11199747 0.65 SMN1; SMN2 (0.52) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL2087376 0.63 ADH1B (0.50) MITFSMN1; SMN2ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111937216-A Additive for nonaqueous electrolyte solution, and electricity storage device 住友精化株式会社 2020-11-13 CN disclosed