SCHEMBL5111267

SCHEMBL5111267

C=CCNC1CCS(=O)(=O)C1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 3/20 0.43
MAPT P10636 1/20 0.43
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4802583 0.78 SMN1; SMN2 (0.48) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL11200026 0.77 SMN1; SMN2 (0.52) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL11199747 0.77 SMN1; SMN2 (0.52) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL12409575 0.74 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1MAPTLMNAGAA
SCHEMBL11817502 0.74 SMN1; SMN2 (0.48) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL469045 0.74 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1MAPTLMNAGAA
SCHEMBL11812131 0.74 SMN1; SMN2 (0.48) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL28532142 0.73 MITF (0.47) MITFSMN1; SMN2ALDH1A1MAPTLMNA
Hydrochloric Acid SCHEMBL11200108 0.72 SMN1; SMN2 (0.52) MITFSMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL11813697 0.72 SMN1; SMN2 (0.47) MITFSMN1; SMN2ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967216-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-11-22 US claimed
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor ASTRAZENECA AB (SE) 2003-12-04 US claimed
CN-122055805-A Super capacitor comprising sulfur-based electrolyte system 京瓷AVX元器件公司 2026-05-15 CN disclosed
US-20250285817-A1 Ultracapacitor for Use in a Solder Reflow Process KYOCERA AVX Components Corporation 2025-09-11 US disclosed
WO-2025085753-A1 ULTRACAPACITOR INCLUDING A SULFUR-BASED ELECTROLYTE SYSTEM KYOCERA AVX Components Corporation (US) 2025-04-24 WO disclosed
US-20250132104-A1 Ultracapacitor Including a Sulfur-Based Electrolyte System KYOCERA AVX Components Corporation 2025-04-24 US disclosed
US-9520617-B2 Sulfolane mixtures as ambient aprotic polar solvents ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2016-12-13 US disclosed
US-20140319423-A1 SULFOLANE MIXTURES AS AMBIENT APROTIC POLAR SOLVENTS ADVANCED TECHNOLOGY MATERIALS, INC (US) 2014-10-30 US disclosed
EP-2778158-A1 Sulfolane mixtures as ambient aprotic polar solvents Advanced Technology Materials, Inc. (US) 2014-09-17 EP disclosed
US-7332492-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2008-02-19 US disclosed
US-6967216-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-11-22 US disclosed
US-20050209233-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-09-22 US disclosed
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor ASTRAZENECA AB (SE) 2003-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209233-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor NPY5R, NPY1R, NPY2R MITF 368/4885SMN1; SMN2 1627/4885ALDH1A1 3658/4885
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor NPY5R, NPY1R, NPY2R MITF 539/4885SMN1; SMN2 1621/4885ALDH1A1 3792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.