Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGAV | P06756 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.31 |
| ▸ | IL2RA | P01589 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | IL2 | P60568 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459589 | 0.94 | ITGB1 (0.34) | CACNA1BITGB1ITGA5PRCPACACB | |
| SCHEMBL17459590 | 0.94 | ITGB1 (0.34) | CACNA1BITGB1ITGA5PRCPACACB | |
| SCHEMBL28532732 | 0.89 | ITGB1 (0.33) | ITGB1ACACBITGA4ITGB7 | |
| SCHEMBL17459559 | 0.87 | KIF11 (0.32) | ITGB1PRCPACACBITGA4ITGB7 | |
| SCHEMBL17459554 | 0.86 | KIFC1 (0.37) | ITGB3ITGA2BACACBMKNK1 | |
| SCHEMBL17945643 | 0.85 | F10 (0.39) | FPR2ITGB3ITGA2BACKR3PRCP | |
| SCHEMBL28532158 | 0.85 | F10 (0.39) | FPR2ITGB3ITGA2BACKR3PRCP | |
| SCHEMBL28532160 | 0.85 | F10 (0.39) | FPR2ITGB3ITGA2BACKR3PRCP | |
| SCHEMBL16306070 | 0.85 | F10 (0.39) | FPR2ITGB3ITGA2BACKR3PRCP | |
| SCHEMBL17834369 | 0.84 | ACACB (0.41) | FPR2ITGB3ITGA2BACKR3PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074820-B | GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457301-A | Novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-03-09 | — | — | CN | disclosed |