SCHEMBL28532188

SCHEMBL28532188

CC1(c2ccc3ccccc3c2)[C@@H](O)CC[C@@H]1O

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 17/20 0.50
SLC6A4 P31645 16/20 0.50
SLC6A2 P23975 5/20 0.44
CYP2D6 P10635 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27755286 0.69 SLC6A3 (0.76) SLC6A3SLC6A4SLC6A2CYP2D6
SCHEMBL11047193 0.69 OPRM1 (0.59) SLC6A3SLC6A4SLC6A2
SCHEMBL13253935 0.69 OPRM1 (0.59) SLC6A3SLC6A4SLC6A2
SCHEMBL13698275 0.69 OPRM1 (0.46) SLC6A3SLC6A4SLC6A2
SCHEMBL13698285 0.69 SLC6A4 (0.57) SLC6A3SLC6A4SLC6A2
SCHEMBL28193567 0.69 SLC6A4 (0.45) SLC6A3SLC6A4SLC6A2
SCHEMBL10300805 0.68 SLC6A4 (0.45) SLC6A3SLC6A4SLC6A2
SCHEMBL26985761 0.68 SLC6A4 (0.45) SLC6A3SLC6A4SLC6A2
SCHEMBL8218431 0.68 SLC6A4 (0.46) SLC6A3SLC6A4SLC6A2
SCHEMBL28490104 0.67 KDM4E (0.53) SLC6A3SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112522329-B Preparation method of optically pure 2, 2-disubstituted-1, 3-cyclopentanediol 中国科学院天津工业生物技术研究所 2021-10-08 CN disclosed
CN-112522329-A Preparation method of optically pure 2, 2-disubstituted-1, 3-cyclopentanediol 中国科学院天津工业生物技术研究所 2021-03-19 CN disclosed