Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855797 | 0.91 | CNR1 (0.47) | MAPK14MAPTGAALMNAPKM | |
| SCHEMBL2859179 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL2861570 | 0.88 | LMNA (0.47) | MAPK14ALDH1A1MAPK1MAPTGAA | |
| SCHEMBL2856225 | 0.86 | ALDH1A1 (0.44) | MAPK14ALDH1A1MAPK1MAPTGAA | |
| SCHEMBL2856513 | 0.86 | TAAR1 (0.51) | ALDH1A1MAPK1MAPTGAALMNA | |
| SCHEMBL2856518 | 0.86 | ALDH1A1 (0.48) | MAPK14ALDH1A1MAPK1MAPTGAA | |
| SCHEMBL2860396 | 0.86 | GAA (0.52) | ALDH1A1MAPK1MAPTGAALMNA | |
| SCHEMBL2861640 | 0.85 | ALDH1A1 (0.45) | MAPK14ALDH1A1MAPK1MAPTGAA | |
| SCHEMBL2852508 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPK1MAPTGAALMNA | |
| SCHEMBL2857467 | 0.85 | ALDH1A1 (0.51) | MAPK14ALDH1A1MAPK1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |