Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857467 | 0.93 | ALDH1A1 (0.51) | ALDH1A1MAPTNPC1GAARAB9A | |
| SCHEMBL2853116 | 0.92 | CNR1 (0.51) | ALDH1A1MAPTTAAR1SPRPOLB | |
| SCHEMBL2860396 | 0.88 | GAA (0.52) | ALDH1A1MAPTNPC1GAARAB9A | |
| SCHEMBL2856518 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTGAARAB9ATAAR1 | |
| SCHEMBL2859179 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL2856416 | 0.86 | ALDH1A1 (0.52) | ALDH1A1MAPTGAARAB9AMAPK1 | |
| SCHEMBL2853296 | 0.85 | MAPK14 (0.47) | ALDH1A1MAPTGAARAB9AMAPK1 | |
| SCHEMBL2854586 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1GAARAB9A | |
| SCHEMBL2861570 | 0.84 | LMNA (0.47) | ALDH1A1MAPTGAARAB9AMAPK1 | |
| SCHEMBL2852544 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |