Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18974091 | 0.87 | KDM4E (0.57) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL29234777 | 0.83 | RAB9A (0.51) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL5479636 | 0.80 | CES2 (0.60) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL1065225 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL14810551 | 0.78 | KDM4E (0.59) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL28533131 | 0.77 | CES2 (0.56) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL9333827 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL11756323 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL4508472 | 0.77 | CES2 (0.64) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4990568 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9APKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313224-A | ATF6 inhibitors and uses thereof | 黑带医疗有限责任公司 | 2021-02-02 | — | — | CN | disclosed |