Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29715729 | 1.00 | CTSL (0.59) | CTSLITGB3ITGA2BSMN1; SMN2NPC1 | |
| SCHEMBL29808622 | 0.89 | CTSL (0.51) | CTSLSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL28532691 | 0.88 | CTSL (0.54) | CTSLITGB3ITGA2BMAPK1DPP4 | |
| SCHEMBL28775133 | 0.88 | PDK1 (0.54) | CTSLITGB3ITGA2BMAPK1P2RX7 | |
| SCHEMBL28532689 | 0.88 | CTSL (0.54) | CTSLITGB3ITGA2BMAPK1DPP4 | |
| SCHEMBL28775136 | 0.88 | PDK1 (0.54) | CTSLITGB3ITGA2BMAPK1P2RX7 | |
| SCHEMBL28775139 | 0.88 | PDK1 (0.54) | CTSLITGB3ITGA2BMAPK1P2RX7 | |
| SCHEMBL16096333 | 0.87 | CTSL (0.55) | CTSLSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL12299752 | 0.86 | CTSL (0.57) | CTSLITGB3ITGA2B | |
| SCHEMBL2441255 | 0.86 | CTSL (0.57) | CTSLITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729004-A | Heterocyclic compounds | 日商泛美克斯股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-112533898-A | Heterocyclic compounds | 日商泛美克斯股份有限公司 | 2021-03-19 | — | — | CN | disclosed |