SCHEMBL28533304

SCHEMBL28533304

Cc1ccc([PH](=O)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
TDP1 Q9NUW8 3/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
POLB P06746 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
HTT P42858 1/20 0.34
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.32
MCL1 Q07820 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.31
PKM P14618 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31353012 0.89 CES2 (0.41) ALDH1A1TDP1TSHRLMNAPRSS1
SCHEMBL28408749 0.80 PRSS1 (0.40) ALDH1A1TDP1TSHRLMNAPRSS1
SCHEMBL988497 0.72 TDP1 (0.41) ALDH1A1TDP1LMNAPOLBSMN1; SMN2
SCHEMBL183975 0.69 ACHE (0.50) ALDH1A1TDP1TSHRLMNASMN1; SMN2
SCHEMBL637774 0.68 MEN1 (0.37) POLBMEN1KMT2A
SCHEMBL31327834 0.67 ACHE (0.52) ALDH1A1TDP1TSHRLMNAHTT
SCHEMBL1304360 0.67 ACHE (0.52) ALDH1A1TDP1TSHRLMNAHTT
SCHEMBL1305177 0.65 ALDH1A1 (0.40) ALDH1A1TDP1ACHE
SCHEMBL601246 0.64 CYP1A2 (0.53) ALDH1A1TDP1TSHRLMNAPRSS1
SCHEMBL30674801 0.64 CYP1A2 (0.53) ALDH1A1TDP1TSHRLMNAPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375102-B Preparation method of visible light catalyzed phosphonylation imidazopyridine compound 郑州大学 2022-05-20 CN disclosed
CN-112375102-A Preparation method of visible light catalyzed phosphonylation imidazopyridine compound 郑州大学 2021-02-19 CN disclosed