Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.71 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.71 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | F11 | P03951 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150306 | 0.83 | LPL (1.00) | LPLLIPGCA2CA1F11 | |
| SCHEMBL28538692 | 0.80 | LPL (0.56) | LPLLIPGCA2CA1F11 | |
| SCHEMBL2482085 | 0.77 | LPL (0.86) | LPLLIPGCA2CA1F11 | |
| SCHEMBL28533343 | 0.74 | LPL (0.67) | LPLLIPGCA2CA1F11 | |
| SCHEMBL29037583 | 0.74 | LPL (0.79) | LPLLIPGCA2CA1F11 | |
| SCHEMBL13667094 | 0.72 | LPL (0.64) | LPLLIPGCA2CA1F11 | |
| SCHEMBL890400 | 0.72 | LPL (0.73) | LPLLIPGCA2CA1F11 | |
| SCHEMBL204921 | 0.71 | ENPP2 (0.73) | LPLLIPGCA2CA1F11 | |
| SCHEMBL112402 | 0.70 | LPL (0.61) | LPLLIPGCA2CA1F11 | |
| SCHEMBL257735 | 0.70 | LPL (1.00) | LPLLIPGCA2CA1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640958-B | Isobenzofuran derivatives, pharmaceutical compositions and formulations thereof, and uses thereof | 镇江圣安医药有限公司 | 2021-03-30 | — | — | CN | disclosed |