SCHEMBL2482085

SCHEMBL2482085

CCc1ccc(-c2ccc(B(O)O)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.86
LIPG Q9Y5X9 7/20 0.86
CA2 P00918 5/20 0.55
CA1 P00915 4/20 0.55
MGLL Q99685 2/20 0.54
TRPV1 Q8NER1 3/20 0.52
F11 P03951 1/20 0.50
EGFR P00533 1/20 0.44
ENPP2 Q13822 2/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150306 0.93 LPL (1.00) LPLLIPGCA2CA1MGLL
SCHEMBL29037583 0.83 LPL (0.79) LPLLIPGCA2CA1MGLL
SCHEMBL257620 0.83 LPL (0.88) LPLLIPGCA2CA1MGLL
SCHEMBL3792599 0.81 MGLL (0.63) LPLLIPGCA2CA1MGLL
SCHEMBL18394607 0.80 CA2 (0.78) LPLLIPGCA2CA1MGLL
SCHEMBL1702558 0.80 TP53 (0.56) LPLLIPGCA2EGFRTSHR
SCHEMBL806835 0.80 CA2 (0.78) LPLLIPGCA2CA1MGLL
SCHEMBL2776957 0.80 TP53 (0.56) LPLLIPGCA2EGFRTSHR
SCHEMBL13667445 0.80 CA2 (0.78) LPLLIPGCA2CA1MGLL
SCHEMBL13454827 0.79 CA1 (0.89) LPLLIPGCA2CA1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2021119249-A1 CYCLOPHILIN D INHIBITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2021-06-17 WO disclosed
US-10113116-B2 Liquid crystal compound and liquid crystal composition employing the same DAXIN MATERIALS CORPORATION (TW) 2018-10-30 US disclosed
US-9795613-B2 GLP-1 receptor modulators CELGENE INTERNATIONAL II SÀRL (CH) 2017-10-24 US disclosed
US-9795613-B2 GLP-1 receptor modulators CELGENE INTERNATIONAL II SÀRL (CH) 2017-10-24 US disclosed
EP-2520575-B1 1,3,4-OXADIAZOLE-2-CARBOXAMIDE COMPOUND GEN INC ASS PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) 2016-11-30 EP disclosed
US-20160228450-A1 NOVEL GLP-1 RECEPTOR MODULATORS RECEPTOS LLC 2016-08-11 US disclosed
US-20160228450-A1 NOVEL GLP-1 RECEPTOR MODULATORS RECEPTOS LLC 2016-08-11 US disclosed
US-20160222295-A1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME DAXIN MATERIALS CORPORATION (TW) 2016-08-04 US disclosed
CN-102725287-B 1,3, 4-oxadiazole-2-carboxamide compounds PHARMA IP GENERAL INC ASS 2015-07-01 CN disclosed
US-7749403-B2 Monofluorinated terphenyl compound having alkenyl, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2010-07-06 US disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2009-08-20 US disclosed
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2009-08-20 US disclosed
WO-2008146720-A1 INDENOCHRYSENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 2008-12-04 WO disclosed
EP-1970362-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2008-09-17 EP disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
US-20040266826-A1 Thiophenylthiopyrane dioxides as mmp or tnf-alpha inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-12-30 US disclosed
EP-1423386-A1 THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-06-02 EP disclosed
WO-2003022842-A1 THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160228450-A1 NOVEL GLP-1 RECEPTOR MODULATORS GLP1R, GIPR, NPY1R LPL 1082/4885LIPG 2028/4885CA2 3950/4885
US-10113116-B2 Liquid crystal compound and liquid crystal composition employing the same ZYX, MLX, NPM1 LPL 993/4885LIPG 2470/4885CA2 2293/4885
US-20040266826-A1 Thiophenylthiopyrane dioxides as mmp or tnf-alpha inhibitors TNF, MMP9, MMP1 LPL 2387/4885LIPG 883/4885CA2 561/4885
US-20160222295-A1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME ZYX, MLX, NPM1 LPL 993/4885LIPG 2470/4885CA2 2293/4885
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, FZD7, HTR1D LPL 2855/4885LIPG 3845/4885CA2 4348/4885
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 LPL 3816/4885LIPG 3010/4885CA2 1992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.