Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23649489 | 0.77 | — | — | |
| SCHEMBL4320020 | 0.71 | ERN1 (0.41) | POLBTDP1ERN1NNMT | |
| SCHEMBL29850137 | 0.68 | POLB (0.50) | POLBTDP1ERN1NNMT | |
| SCHEMBL1460108 | 0.68 | POLB (0.50) | POLBTDP1ERN1NNMT | |
| SCHEMBL5775323 | 0.66 | POLB (0.36) | POLBTDP1NNMT | |
| SCHEMBL2969903 | 0.66 | CYP1A2 (0.41) | POLBTDP1NNMTTXNRD1 | |
| SCHEMBL30207735 | 0.66 | CYP1A2 (0.41) | POLBTDP1NNMTTXNRD1 | |
| SCHEMBL21046505 | 0.65 | L3MBTL1 (0.37) | POLBTDP1NNMT | |
| SCHEMBL1712251 | 0.65 | ERN1 (0.46) | POLBTDP1ERN1 | |
| SCHEMBL1461146 | 0.64 | NNMT (0.48) | POLBTDP1NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128432-B | Nitrogenous tricyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-107686486-B | Nitrogenous tricyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | disclosed |