Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616595 | 0.92 | SRD5A2 (0.38) | SRD5A2LPLLIPGLTA4HKDM2B | |
| SCHEMBL28526814 | 0.89 | SRD5A2 (0.39) | SRD5A2LIPGF2RLTA4HP2RY14 | |
| SCHEMBL28542508 | 0.88 | SRD5A2 (0.38) | SRD5A2F2RLTA4HNOTUMP2RY14 | |
| SCHEMBL28532617 | 0.87 | LIPC (0.40) | SRD5A2LIPGF2RLTA4HKDM2B | |
| SCHEMBL28910599 | 0.87 | P2RY14 (0.37) | SRD5A2F2RLTA4HKDM2BP2RY14 | |
| SCHEMBL28910602 | 0.87 | FPR1 (0.41) | SRD5A2F2RLTA4HNOTUMP2RY14 | |
| SCHEMBL28533648 | 0.86 | P2RY14 (0.43) | SRD5A2LIPGF2RP2RY14CCR2 | |
| SCHEMBL28532591 | 0.86 | SRD5A2 (0.36) | SRD5A2F2RLTA4HP2RY14ADRA2A | |
| SCHEMBL28537090 | 0.85 | PTGIR (0.40) | LPLLIPGF2RP2RY14ADRA2A | |
| SCHEMBL23631891 | 0.85 | SRD5A2 (0.39) | SRD5A2F2RLTA4HNOTUMP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |