Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 3/20 | 0.43 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 4/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910599 | 0.91 | P2RY14 (0.37) | P2RY14F2RSRD5A2KDM4EALDH1A1 | |
| SCHEMBL28910602 | 0.91 | FPR1 (0.41) | P2RY14F2RSRD5A2KDM4EALDH1A1 | |
| SCHEMBL28542508 | 0.90 | SRD5A2 (0.38) | P2RY14F2RSRD5A2PTGER4CCR2 | |
| SCHEMBL28532617 | 0.90 | LIPC (0.40) | P2RY14LIPCLIPGF2RSRD5A2 | |
| SCHEMBL28526814 | 0.89 | SRD5A2 (0.39) | P2RY14LIPGF2RSRD5A2KDM4E | |
| SCHEMBL28532591 | 0.89 | SRD5A2 (0.36) | P2RY14F2RSRD5A2DRD3PTGER4 | |
| SCHEMBL28533463 | 0.86 | SRD5A2 (0.38) | P2RY14LIPGF2RSRD5A2KDM4E | |
| SCHEMBL28537013 | 0.84 | ELANE (0.36) | P2RY14HTT | |
| SCHEMBL21616610 | 0.84 | SRD5A2 (0.38) | P2RY14F2RSRD5A2KDM4EALDH1A1 | |
| SCHEMBL23631891 | 0.83 | SRD5A2 (0.39) | P2RY14F2RSRD5A2PTGER4CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |