Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848886 | 0.94 | ALDH1A1 (0.45) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL28532225 | 0.91 | HTT (0.43) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL801917 | 0.85 | SMN1; SMN2 (0.48) | EPHX2ALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL17848824 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL11964211 | 0.84 | L3MBTL1 (0.47) | EPHX2ALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL25172376 | 0.78 | ALDH1A1 (0.57) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL11124646 | 0.78 | ALDH1A1 (0.57) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL22819559 | 0.78 | ALDH1A1 (0.57) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL7094905 | 0.78 | ALDH1A1 (0.57) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL772826 | 0.78 | ALDH1A1 (0.57) | EPHX2ALDH1A1MAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107257803-B | Polymyxin antibacterial agents for the treatment of bacterial infections | 上海盟科药业股份有限公司 | 2021-02-05 | — | — | CN | disclosed |