Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.34 |
| ▸ | TUBB | P07437 | 5/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017593 | 0.86 | ALOX5 (0.39) | ALOX5KMT2AMEN1KDM4EMAPT | |
| SCHEMBL2014416 | 0.69 | CLK1 (0.32) | ALOX5KMT2AMEN1MAPK1GAA | |
| SCHEMBL2017601 | 0.69 | MCL1 (0.40) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL28537384 | 0.67 | S1PR1 (0.52) | — | |
| SCHEMBL4036458 | 0.66 | KDM4E (0.39) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL4036453 | 0.66 | KDM4E (0.39) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL946033 | 0.66 | NTRK1 (0.35) | POLBKDM2B | |
| SCHEMBL18052982 | 0.63 | TUBB1 (0.41) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL2016666 | 0.62 | S1PR1 (0.41) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL18054329 | 0.62 | ALDH1A1 (0.43) | MAPTALDH1A1POLBHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105816453-B | Substituted tricyclic acid derivatives as S1P1 receptor agonists for the treatment of autoimmune and inflammatory disorders | 艾尼纳制药公司 | 2021-03-05 | — | — | CN | disclosed |