Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893876 | 0.85 | KCNK2 (0.57) | KCNK2MPOKEAP1FABP3FABP4 | |
| SCHEMBL9200144 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4E | |
| SCHEMBL252578 | 0.78 | KDM4E (0.65) | KCNK2MPOKEAP1FABP3FABP4 | |
| SCHEMBL7541890 | 0.78 | KEAP1 (0.55) | KCNK2MPOKEAP1FABP3FABP4 | |
| SCHEMBL7836703 | 0.78 | PTPN1 (0.65) | KCNK2MPOKEAP1FABP3FABP4 | |
| SCHEMBL9000255 | 0.77 | FABP3 (0.61) | KCNK2MPOKEAP1FABP3FABP4 | |
| SCHEMBL14854009 | 0.76 | PDK1 (0.42) | ALDH1A1GAAKDM4EGRIK1 | |
| SCHEMBL19980681 | 0.75 | KEAP1 (0.60) | KCNK2MPOKEAP1FABP3FABP4 | |
| SCHEMBL16854334 | 0.74 | KDM4E (0.55) | KCNK2MPOKEAP1ALDH1A1GAA | |
| SCHEMBL8484239 | 0.74 | KCNK2 (0.49) | KCNK2MPOKEAP1FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441989-B | Preparation method and application of flumazenil intermediate 5-fluoroisatoic anhydride | 江苏恩华药业股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-112441989-A | Preparation method and application of flumazenil intermediate 5-fluoroisatoic anhydride | 江苏恩华药业股份有限公司 | 2021-03-05 | — | — | CN | disclosed |