Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802165 | 0.85 | CES2 (0.50) | NPC1RAB9AMEN1KMT2AELANE | |
| SCHEMBL700922 | 0.81 | METAP2 (0.58) | NPC1RAB9AMETAP2MEN1KMT2A | |
| SCHEMBL27675448 | 0.81 | METAP2 (0.58) | NPC1RAB9AMETAP2MEN1KMT2A | |
| SCHEMBL31058978 | 0.79 | MEN1 (0.47) | NPC1RAB9AMEN1KMT2AELANE | |
| SCHEMBL29046760 | 0.79 | METAP2 (0.56) | NPC1RAB9AMETAP2MEN1KMT2A | |
| SCHEMBL4880477 | 0.79 | METAP2 (0.56) | NPC1RAB9AMETAP2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4383251 | 0.79 | METAP2 (0.56) | NPC1RAB9AMETAP2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4100040 | 0.79 | METAP2 (0.56) | NPC1RAB9AMETAP2MEN1KMT2A | |
| SCHEMBL5349768 | 0.79 | MEN1 (0.47) | NPC1RAB9AMEN1KMT2AELANE | |
| SCHEMBL31162480 | 0.78 | NPC1 (0.42) | NPC1RAB9AMETAP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698407-B | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2022-11-29 | — | — | CN | claimed |
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | claimed |
| CN-110183379-B | Synthesis method and application of copper-catalyzed one-pot method for preparing C-4-sulfonyl substituted isoquinolone compounds | 青岛科技大学 | 2021-02-05 | — | — | CN | claimed |
| CN-113698407-B | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | disclosed |