SCHEMBL700922

SCHEMBL700922

NC(=O)c1ccccc1Br

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.58
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
MAPT P10636 2/20 0.56
TSHR P16473 2/20 0.56
HSD17B10 Q99714 2/20 0.56
HPGD P15428 1/20 0.56
BCAT2 O15382 1/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
GAA P10253 1/20 0.45
CTNNB1 P35222 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ELANE P08246 1/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4100040 0.98 METAP2 (0.56) METAP2KDM4EALDH1A1MAPTTSHR
SCHEMBL4880477 0.98 METAP2 (0.56) METAP2KDM4EALDH1A1MAPTTSHR
SCHEMBL29046760 0.98 METAP2 (0.56) METAP2KDM4EALDH1A1MAPTTSHR
Hydrochloric Acid SCHEMBL4383251 0.98 METAP2 (0.56) METAP2KDM4EALDH1A1MAPTTSHR
Hydrochloric Acid SCHEMBL4100039 0.95 METAP2 (0.54) METAP2KDM4EALDH1A1MAPTTSHR
SCHEMBL29941064 0.82 BCAT2 (0.59) METAP2KDM4EALDH1A1MAPTTSHR
SCHEMBL1898665 0.82 BCAT2 (0.59) METAP2KDM4EALDH1A1MAPTTSHR
Acrylic Acid SCHEMBL28948916 0.82 HPGD (0.42) METAP2KDM4EALDH1A1MAPTTSHR
SCHEMBL3170417 0.81 METAP2 (0.48) METAP2KDM4EALDH1A1MAPTTSHR
SCHEMBL28533872 0.81 NPC1 (0.44) METAP2KDM4EALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652285-A Preparation method of trisubstituted ferrocene derivative 华侨大学 2024-09-17 CN claimed
CN-118084713-A Perovskite solar cell multifunctional molecular additive and preparation method and application thereof 正泰新能科技股份有限公司 2024-05-28 CN claimed
CN-107674068-B Method for synthesizing chlorantraniliprole derivative intermediate 浙江工业大学 2023-12-19 CN claimed
CN-117110458-A Method for detecting halogenated benzamide by solid phase extraction-liquid chromatography tandem mass spectrometry 浙江工业大学 2023-11-24 CN claimed
CN-116554100-A Method for synthesizing phenanthridinone compound by palladium catalysis 江苏师范大学 2023-08-08 CN claimed
CN-116375549-A Method and system for synthesizing amide compound from nitrile compound 深圳湾实验室 2023-07-04 CN claimed
CN-115662691-A Sectional type moisture-proof cable and preparation method thereof 刘启铃 2023-01-31 CN claimed
CN-113698407-B Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction 武汉科技大学 2022-11-29 CN claimed
CN-115073506-A Supported alpha-diimine nickel catalyst and preparation and application of ligand thereof 中国科学技术大学 2022-09-20 CN claimed
CN-113072543-B 2-aromatic heterocyclic quinazoline ketone compound and preparation method and application thereof 南方医科大学 2022-07-22 CN claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
EP-0751123-B1 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 2000-05-10 EP claimed
US-5672751-A TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-09-30 US claimed
EP-0751123-A2 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-01-02 EP claimed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP claimed
US-4942232-A FOR PRINTING AND DYEING CELLULOSE FIBERS BASF AKTIENGESELLSCHAFT (DE) 1990-07-17 US claimed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US claimed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US claimed
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed