Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14682858 | 0.82 | HPGD (0.68) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL51173 | 0.81 | CYP3A4 (0.67) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL561006 | 0.79 | CYP3A4 (0.52) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL384040 | 0.78 | IDO1 (0.44) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL30089455 | 0.78 | IDO1 (0.44) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL269324 | 0.77 | HTR2A (0.41) | CYP3A4HPGDMEN1KMT2AHIF1A | |
| SCHEMBL1005910 | 0.77 | HSD17B10 (0.50) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL18551328 | 0.77 | HSD17B10 (0.50) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL21910193 | 0.77 | GABRA1 (0.48) | CYP3A4HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL23214736 | 0.76 | HSD17B10 (0.48) | CYP3A4HSD17B10HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001309-B | Bis (sulfonamide) derivatives and their use as MPGES inhibitors | 格辛塔制药公司 | 2021-03-05 | — | — | CN | disclosed |