Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637021 | 0.83 | TYR (0.50) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL364080 | 0.82 | HIF1A (0.68) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL51173 | 0.81 | CYP3A4 (0.67) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL25852925 | 0.79 | MEN1 (0.44) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL11683860 | 0.79 | TYR (0.67) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL561006 | 0.79 | CYP3A4 (0.52) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL2394432 | 0.78 | KEAP1 (0.53) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| Benzene SCHEMBL574407 | 0.78 | HIF1A (0.63) | HSD17B10CYP3A4MEN1KMT2AHIF1A | |
| SCHEMBL3782085 | 0.78 | IDO1 (0.44) | CYP3A4MEN1KMT2AHIF1AHPGD | |
| SCHEMBL28534044 | 0.77 | CYP3A4 (0.50) | HSD17B10CYP3A4MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106542968-A | The synthetic method of 2 ethyl of medical raw material, 5 chlorophenol | 无锡乾浩生物医药有限公司 | 2017-03-29 | — | — | CN | claimed |
| US-4004033-A | GRAMNEGATIVE BACTERIA, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | claimed |
| US-12421349-B2 | Polyphenylene ether composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-09-23 | — | — | US | disclosed |
| CN-114514261-B | Polyphenylene ether composition | 旭化成株式会社 | 2024-09-10 | — | — | CN | disclosed |
| CN-117229495-A | Polyphenylene ether, method for producing the same, thermosetting composition, prepreg, and laminate | 旭化成株式会社 | 2023-12-15 | — | — | CN | disclosed |
| EP-4039728-B1 | POLYPHENYLENE ETHER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-112812291-B | Hydrogenated polyphenylene ether and process for producing the same | 旭化成株式会社 | 2023-07-18 | — | — | CN | disclosed |
| US-20230151007-A1 | SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-05-18 | — | — | US | disclosed |
| WO-2022239631-A1 | NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION | 旭化成株式会社 | 2022-11-17 | — | — | WO | disclosed |
| US-20220356302-A1 | POLYPHENYLENE ETHER COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2022-11-10 | — | — | US | disclosed |
| EP-4039728-A1 | POLYPHENYLENE ETHER COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2022-08-10 | — | — | EP | disclosed |
| US-20100069425-A1 | GLUCOCORTICOID RECEPTOR MODULATOR AND METHODS OF USE | ELI LILLY AND COMPANY (US) | 2010-03-18 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-5350827-A | Photoresists in monolithographic process for photosensitive elements | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5338652-A | Coating substrate with mixture of novolak resins and o-quinonediazide for positive resist having improved resolution, then exposure, development | OCG MICROELECTRONIC MARTERIALS, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| US-5306594-A | Positive working photoresist | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1994-04-26 | — | — | US | disclosed |
| WO-1993009473-A1 | SELECTED STRUCTURALLY DEFINED NOVOLAK BINDER RESINS | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | HSD17B10 346/4885CYP3A4 952/4885MEN1 4091/4885 |
| US-20230151007-A1 | SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | DGKZ, DGKA, DGKG | HSD17B10 4409/4885CYP3A4 3960/4885MEN1 3171/4885 |
| US-20100069425-A1 | GLUCOCORTICOID RECEPTOR MODULATOR AND METHODS OF USE | NR3C1, NR3C2, MC2R | HSD17B10 531/4885CYP3A4 880/4885MEN1 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.