Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538299 | 0.90 | SIGMAR1 (0.41) | SIGMAR1GAAEBPTAAR1CNR2 | |
| SCHEMBL1538360 | 0.88 | SIGMAR1 (0.41) | SIGMAR1GAAEBPTAAR1CNR2 | |
| SCHEMBL813383 | 0.88 | TAAR1 (0.41) | LMNASIGMAR1TAAR1KCNN4KIF11 | |
| SCHEMBL1538329 | 0.87 | HDAC3 (0.35) | LMNASIGMAR1EBPCNR2CNR1 | |
| SCHEMBL22972830 | 0.86 | SIGMAR1 (0.40) | SIGMAR1GAAEBPTAAR1CNR2 | |
| SCHEMBL1538361 | 0.84 | KIF11 (0.41) | LMNASIGMAR1TAAR1KCNN4CHRM2 | |
| Hexane SCHEMBL28962140 | 0.83 | TAAR1 (0.44) | LMNASIGMAR1TAAR1KCNN4MAPK1 | |
| SCHEMBL1538270 | 0.81 | TAAR1 (0.46) | LMNATAAR1KCNN4KMT2AMAPK1 | |
| SCHEMBL26971617 | 0.80 | ALDH1A1 (0.39) | LMNATAAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL15524994 | 0.80 | CNR2 (0.38) | SIGMAR1GAAEBPCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698766-B | Branched polyorganosiloxanes and related curable compositions, methods, uses and devices | 美国陶氏有机硅公司 | 2021-02-23 | — | — | CN | disclosed |