Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | YWHAG | P61981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644575 | 0.84 | MAPT (0.55) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL15652434 | 0.84 | MAPT (0.56) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL2979005 | 0.75 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL2968786 | 0.74 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL28901605 | 0.74 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL28022083 | 0.72 | ALDH1A1 (0.70) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL26151702 | 0.71 | ADRB2 (0.36) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL9367414 | 0.70 | GAA (0.40) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL31533760 | 0.69 | GAA (0.39) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL6310104 | 0.69 | GAA (0.39) | ALDH1A1POLBMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836819-A | Arylamine-substituted pyrrolopyrimidine compound, and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |