SCHEMBL2853463

SCHEMBL2853463

C=C(C)C(=O)OOC(=O)CC(=O)CCC

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.38
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL16094105 0.93 TSHR (0.37) ALDH1A1THRBTSHR
SCHEMBL15329266 0.84 ALDH1A1 (0.46) ALDH1A1THRBTSHRMGAMGAA
SCHEMBL727178 0.78 ALDH1A1 (0.48) ALDH1A1THRBTSHRMGAMGAA
SCHEMBL8641857 0.76 TSHR (0.42) ALDH1A1THRBTSHRHDAC3HDAC1
SCHEMBL27722645 0.76 ALDH1A1 (0.44) ALDH1A1THRBTSHRMGAMGAA
SCHEMBL6292365 0.74 MGAM (0.40) ALDH1A1THRBTSHRMGAMGAA
SCHEMBL3844764 0.74 TSHR (0.55) ALDH1A1TSHRCES2CES1
SCHEMBL7761909 0.74 TSHR (0.55) ALDH1A1TSHRCES2CES1
SCHEMBL27686811 0.73 TSHR (0.44) ALDH1A1THRBTSHR
SCHEMBL4138390 0.72 ALDH1A1 (0.41) ALDH1A1TSHRMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010144348-A2 REDUCTION OF ANTIBIOTIC ACTIVITY OR CONCENTRATION IN BIOLOGICAL SAMPLES USING MOLECULARLY IMPRINTED POLYMERS BECTON, DICKINSON AND COMPANY (US) 2010-12-16 WO disclosed