Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265506 | 1.00 | ALDH1A1 (0.58) | ALDH1A1RAB9APTPN1POLBPRSS1 | |
| SCHEMBL1427713 | 1.00 | ALDH1A1 (0.58) | ALDH1A1RAB9APTPN1POLBPRSS1 | |
| SCHEMBL9829285 | 0.86 | RAB9A (0.60) | ALDH1A1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL3948327 | 0.86 | RAB9A (0.60) | ALDH1A1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL10659467 | 0.86 | MEN1 (0.54) | ALDH1A1RAB9APTPN1POLBL3MBTL1 | |
| SCHEMBL26263205 | 0.84 | ALDH1A1 (0.54) | ALDH1A1PTPN1POLBL3MBTL1LMNA | |
| SCHEMBL31446720 | 0.84 | ALDH1A1 (0.58) | ALDH1A1PTPN1L3MBTL1NPC1LMNA | |
| SCHEMBL8140150 | 0.84 | KDM4E (0.50) | ALDH1A1PTPN1L3MBTL1GPR132 | |
| SCHEMBL3679721 | 0.84 | RAB9A (0.59) | ALDH1A1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL18196146 | 0.84 | RAB9A (0.50) | ALDH1A1RAB9APTPN1PRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264566-A1 | ANTI-ALPHAVBETA1 INTEGRIN INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-09-15 | — | — | US | disclosed |
| WO-2010019469-A2 | PREPARATION OF (S)-2-AMINOBUTYRIC ACID | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010019469-A2 | PREPARATION OF (S)-2-AMINOBUTYRIC ACID | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264566-A1 | ANTI-ALPHAVBETA1 INTEGRIN INHIBITORS AND METHODS OF USE | ITGB1, ITGA1, ITGAV | ALDH1A1 735/4885RAB9A 780/4885PTPN1 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.