SCHEMBL28534779

SCHEMBL28534779

OCCCCC(O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.47
SRD5A2 P31213 1/20 0.46
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42
TSHR P16473 1/20 0.41
RIPK1 Q13546 1/20 0.40
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
NPY5R Q15761 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5145618 0.87 AOC3 (0.38) LTA4HSRD5A2ALDH1A1LMNAHPGD
SCHEMBL28532338 0.85 PTGS1 (0.49) LTA4HALDH1A1LMNAHPGDTSHR
SCHEMBL1308572 0.83 RIPK1 (0.53) ALDH1A1LMNARIPK1
SCHEMBL9579891 0.83 RIPK1 (0.53) ALDH1A1LMNARIPK1
SCHEMBL9050231 0.83 LTA4H (0.58) LTA4HSRD5A2ALDH1A1LMNARIPK1
SCHEMBL29211080 0.81 RIPK1 (0.52) ALDH1A1LMNARIPK1
SCHEMBL29211135 0.81 RIPK1 (0.52) ALDH1A1LMNARIPK1
SCHEMBL29211140 0.81 RIPK1 (0.52) ALDH1A1LMNARIPK1
SCHEMBL21371750 0.81 RIPK1 (0.52) ALDH1A1LMNARIPK1
SCHEMBL8618795 0.81 RIPK1 (0.52) ALDH1A1LMNARIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111954539-B Mitochondrial targeting peptides 隐形生物治疗公司 2024-06-21 CN disclosed
CN-117624286-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-03-01 CN disclosed
CN-111954539-A Mitochondrial targeting peptides 隐形生物治疗公司 2020-11-17 CN disclosed