Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317645 | 0.93 | LTA4H (0.48) | LTA4HALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL14402503 | 0.85 | PTGS1 (0.53) | LTA4HALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL12896704 | 0.84 | LMNA (0.67) | LTA4HSRD5A2LMNA | |
| Fenipentol SCHEMBL11573151 | 0.83 | LMNA (0.64) | ALDH1A1KDM4ELMNARIPK1SMN1; SMN2 | |
| Fenipentol SCHEMBL11351770 | 0.83 | LMNA (0.64) | ALDH1A1KDM4ELMNARIPK1SMN1; SMN2 | |
| Fenipentol SCHEMBL21837 | 0.83 | LMNA (0.64) | ALDH1A1KDM4ELMNARIPK1SMN1; SMN2 | |
| SCHEMBL11496449 | 0.83 | SIGMAR1 (0.51) | LTA4HALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28534779 | 0.83 | LTA4H (0.47) | LTA4HALDH1A1SRD5A2LMNAGAA | |
| SCHEMBL11534496 | 0.83 | SRD5A2 (0.46) | LTA4HALDH1A1SRD5A2MAPTLMNA | |
| SCHEMBL11433536 | 0.82 | HTR2A (0.53) | LTA4HALDH1A1KDM4ESRD5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |