Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537171 | 0.87 | SCN9A (0.46) | SCN9ALMNAS1PR3 | |
| SCHEMBL28544156 | 0.83 | LMNA (0.48) | SCN9ALMNAS1PR3SLC6A9PTGDR2 | |
| SCHEMBL28544660 | 0.81 | LMNA (0.46) | LMNAS1PR3SLC6A9PTGDR2KCNH2 | |
| SCHEMBL2825364 | 0.80 | SLC6A9 (0.51) | LMNAS1PR3SLC6A9PTGDR2KCNH2 | |
| SCHEMBL28911175 | 0.80 | SCN9A (0.42) | SCN9APTGDR2 | |
| SCHEMBL28535194 | 0.79 | SLC6A9 (0.44) | SCN9ALMNAS1PR3SLC6A9PTGDR2 | |
| SCHEMBL28543014 | 0.79 | LMNA (0.44) | LMNAS1PR3SLC6A9PTGDR2KCNH2 | |
| SCHEMBL3873094 | 0.78 | SLC6A9 (0.56) | LMNAS1PR3SLC6A9PTGDR2KCNH2 | |
| SCHEMBL1814036 | 0.78 | LMNA (0.48) | LMNAS1PR3SLC6A9PTGDR2KCNH2 | |
| SCHEMBL5179978 | 0.77 | S1PR3 (0.55) | LMNAS1PR3SLC6A9PTGDR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105712952-B | 2-substituted oxy-5-methylsulfonyl phenyl piperazine amide analogue and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-26 | — | — | CN | disclosed |