SCHEMBL28534875

SCHEMBL28534875

CC(C)C1CC=C(COC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
NPC1 O15118 1/20 0.42
PTPN2 P17706 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPN6 P29350 1/20 0.40
PTPN11 Q06124 1/20 0.40
GAA P10253 2/20 0.38
HTT P42858 1/20 0.38
ALOX5 P09917 2/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674285 0.81 ALDH1A1 (0.46) CES2NPC1PTPN2PTPN1PTPN6
SCHEMBL674777 0.81 ALDH1A1 (0.46) CES2NPC1PTPN2PTPN1PTPN6
SCHEMBL12324194 0.76 ALDH1A1 (0.45) CES2NPC1ALDH1A1MAPK1
SCHEMBL28528027 0.75 PTPN1 (0.52) CES2PTPN1ALDH1A1MAPK1
SCHEMBL17907537 0.74 NPC1 (0.44) NPC1PTPN2PTPN1PTPN6PTPN11
SCHEMBL674829 0.70 ALDH1A1 (0.46) CES2MEN1KMT2AALDH1A1MAPT
SCHEMBL27764131 0.70 NPC1 (0.56) NPC1PTPN2PTPN1PTPN6PTPN11
SCHEMBL1114367 0.68 NPC1 (0.79) NPC1PTPN2PTPN1PTPN6PTPN11
SCHEMBL5708190 0.68 SMN1; SMN2 (0.57) NPC1PTPN2PTPN1PTPN6PTPN11
SCHEMBL7908561 0.68 NPC1 (0.54) NPC1PTPN2PTPN1PTPN6PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105616391-B Method and apparatus for using isoperillyl alcohol 尼昂克技术公司 2021-03-19 CN disclosed