SCHEMBL674829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL674777	0.89	ALDH1A1 (0.46)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL674285	0.89	ALDH1A1 (0.46)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL674176	0.84	ALOX15 (0.50)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL678301	0.83	ALDH1A1 (0.49)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL26300887	0.80	CES2 (0.47)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL4785327	0.77	ALOX15 (0.50)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL1302136	0.77	ALOX15 (0.62)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL10081724	0.75	ALOX15 (0.59)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL19919386	0.75	ALOX15 (0.62)	ALDH1A1ALOX15CYP1B1CES2MAPK1
	SCHEMBL16774726	0.75	ALOX15 (0.59)	ALDH1A1ALOX15CYP1B1CES2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.