Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23044983 | 0.75 | KDM4E (0.52) | DHODHCYP1A2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8687449 | 0.74 | NQO2 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13223636 | 0.74 | NPC1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8688747 | 0.72 | KDM4E (0.43) | DHODHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL619001 | 0.72 | DCPS (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23612605 | 0.71 | NQO2 (0.68) | NPC1RAB9AELANEPOLBMAPT | |
| SCHEMBL28900198 | 0.71 | PDE10A (0.52) | DHODHGPR35NPC1RAB9APOLB | |
| SCHEMBL8569649 | 0.70 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10516310 | 0.70 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3898412 | 0.70 | RAB9A (0.58) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239889-A | Acridone compound and medical application thereof as STING inhibitor | 中国人民解放军军事科学院军事医学研究院 | 2024-06-25 | — | — | CN | disclosed |
| CN-112624972-A | Acridone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-04-09 | — | — | CN | disclosed |
| CN-112442033-A | STING pathway modulators and uses thereof | 迈德欣国际有限公司 | 2021-03-05 | — | — | CN | disclosed |