Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969068 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10POLBHPGD | |
| SCHEMBL23044983 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1CYP2C9HSD17B10POLB | |
| SCHEMBL3898415 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1CYP2C9POLBCYP2D6 | |
| SCHEMBL8687449 | 0.75 | NQO2 (0.53) | KDM4EALDH1A1POLBHPGDGAA | |
| SCHEMBL6584881 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10POLBHPGD | |
| SCHEMBL28534944 | 0.72 | CA12 (0.46) | KDM4EALDH1A1CYP2C9POLBHPGD | |
| Hydrochloric Acid SCHEMBL7531424 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10POLBHPGD | |
| SCHEMBL3895839 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1CYP2C9POLBCYP2D6 | |
| SCHEMBL13223650 | 0.70 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10POLBHPGD | |
| SCHEMBL10902014 | 0.70 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723295-A | MULTISTAGE CHEMILUMINESCENT ASSAY WITH PEROXIDASE ENZYME, PH ADJUSTMENT | LUMIGEN, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5670644-A | CHEMILUMINESCENT REACTIONS, PEROXIDASE AND PH FOR IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-09-23 | — | — | US | disclosed |