Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851440 | 0.80 | LMNA (0.48) | KDM4EMAPTNPC1RAB9ACASP3 | |
| SCHEMBL6285594 | 0.75 | GAA (0.41) | KDM4EMAPTPDGFRBALDH1A1THRB | |
| SCHEMBL7104266 | 0.75 | PDGFRB (0.38) | KDM4EMAPTPDGFRBALDH1A1HPGD | |
| SCHEMBL11868181 | 0.74 | KDM4E (0.43) | KDM4EMAPTNPC1RAB9APDGFRB | |
| SCHEMBL10850884 | 0.70 | SIGMAR1 (0.56) | — | |
| SCHEMBL6285586 | 0.70 | ACVR1 (0.40) | KDM4EMAPTPDGFRBALDH1A1HPGD | |
| SCHEMBL6310414 | 0.68 | MAP2K1 (0.62) | KDM4EMAPTNPC1RAB9ACASP3 | |
| SCHEMBL1515037 | 0.67 | CA1 (0.52) | KDM4EMAPTNPC1RAB9ACASP3 | |
| SCHEMBL16090218 | 0.66 | ALDH1A1 (0.44) | KDM4EMAPTPDGFRBALDH1A1HPGD | |
| SCHEMBL28803678 | 0.66 | ABL1 (0.46) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107496419-B | Cyclopenta [ b ] pyrrole compound with anti-inflammatory activity | 兰州大学 | 2021-03-23 | — | — | CN | disclosed |