Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7902877 | 0.94 | LMNA (0.77) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Acetic Acid SCHEMBL9177085 | 0.94 | LMNA (0.77) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Acetic Acid SCHEMBL7908727 | 0.92 | LMNA (0.74) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Phosphoric Acid SCHEMBL28527448 | 0.92 | LMNA (0.79) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Acetic Acid SCHEMBL2108732 | 0.85 | LMNA (0.72) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Acetic Acid SCHEMBL28018617 | 0.85 | LMNA (0.72) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Methyl Alcohol SCHEMBL27642901 | 0.84 | LMNA (0.89) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| SCHEMBL28527433 | 0.84 | LMNA (0.89) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Benzene SCHEMBL27538628 | 0.84 | LMNA (0.96) | LMNACYP3A4ALDH1A1MAPTKDM4E | |
| Methyl Alcohol SCHEMBL27878296 | 0.82 | LMNA (0.85) | LMNACYP3A4ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848663-B | Non-metal organic complex salt of phenanthroline and phenanthroline derivative, and preparation method and application thereof | 西南大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-111848663-A | Non-metal organic complex salt of phenanthroline and phenanthroline derivative, and preparation method and application thereof | 西南大学 | 2020-10-30 | — | — | CN | disclosed |