Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528279 | 0.82 | CYP2D6 (0.38) | OPRM1OPRK1NOS1 | |
| SCHEMBL28528284 | 0.82 | CYP2D6 (0.38) | OPRM1OPRK1NOS1 | |
| SCHEMBL24775580 | 0.78 | HRH3 (0.38) | OPRM1OPRK1 | |
| SCHEMBL28534879 | 0.76 | OPRM1 (0.39) | OPRM1OPRK1 | |
| SCHEMBL28538296 | 0.75 | ALDH1A1 (0.39) | OPRM1OPRK1 | |
| SCHEMBL28529794 | 0.74 | HTR2C (0.41) | — | |
| SCHEMBL31525091 | 0.74 | HTR2C (0.41) | — | |
| SCHEMBL28529792 | 0.74 | HTR2C (0.41) | — | |
| SCHEMBL28909558 | 0.74 | HRH3 (0.41) | CHRNB2CHRNA4OPRM1OPRK1 | |
| SCHEMBL28909552 | 0.74 | HRH3 (0.41) | CHRNB2CHRNA4OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |